President Alpha Condé : The Ebola virus vaccine is effective. But the fight goes on. We must move quickly towards full-scale production...................

Source  WHO NEWS

Conakry (Guinea), 17 August 2015 (WHO):-The President of Guinea, Mr Alpha Condé, called a meeting with Dr Mohamed Belhocine, the WHO Country Representative in Guinea, the coordinator of the Ebola vaccine trial and the CDC/Atlanta coordinator in Guinea. This team of partners was introduced by the national Ebola virus disease coordinator Dr Sakoba Keita.

The conversation focused on the way forward for the Ebola vaccine trial, following the publication by WHO of the preliminary results. The Head of State congratulated WHO for developing a high-quality vaccine in such a short space of time and with such scientific rigour.

High-level expert meeting
The President was keen to stress that the Ebola vaccine is 100% effective, as the trial had shown. But the fight should go on. It was necessary to move quickly towards full-scale production of the vaccine to benefit the whole population. It was important to keep faith. Accordingly, the President proposed that an expert meeting be convened as soon as possible to identify appropriate strategies and organize a high-level meeting of heads of state and government to mobilize resources and political support. The President asked the experts from WHO and CDC for practical suggestions.

The vaccine trial will continue but decisions will be taken by the committee of experts
The WHO Country Representative in Guinea said that the vaccine was an effective additional weapon that would help to break the chain of transmission of the epidemic through the immediate vaccination of contacts (within 24 hours), the contacts of contacts and front-line health workers. Dr Belhocine further explained that other interventions such as contact tracing, active case-finding, medical treatment and safe and dignified burials were all essential.

The vaccine trial coordinator Dr Ana Maria Restrepo said that the trial would continue, thereby ensuring that the committee of experts had all the data at its disposal to make appropriate recommendations on technical matters and decide upon the conditions of use of this new large-scale vaccine. She informed the Head of State that WHO was doing everything it could to expedite the licensing process, and that the GAVI Alliance had already allocated a budget of US$ 380 million to fund production of the vaccine for affected countries.

Doses of vaccine still available
The representative of CDC/Atlanta Dr Pierre Rolin said that, as part of the vaccine trial, Guinea currently had 10 000 does of Ebola virus vaccine for immunization of contacts and 2000 doses for health workers.

A technical committee for Guinea
Following the meeting with the experts from WHO, CDC and the national coordination team, the President gave instructions for the establishment of a technical committee for Guinea, tasked with making proposals and recommendations for organizing a national meeting of experts on Ebola virus vaccine and expediting the production of the vaccine to halt the scourge of Ebola in Africa.

  • WHO calls for urgent action to curb hepatitis...................

    News release 23 JULY 2015 ¦ GENEVA

    On World Hepatitis Day (28 July) WHO highlights the urgent need for countries to enhance action to prevent viral hepatitis infection and to ensure that people who have been infected are diagnosed and offered treatment. This year, the Organization is focusing particularly on hepatitis B and C, which together cause approximately 80% of all liver cancer deaths and kill close to 1.4 million people every year.

    • Know the risks


      WHO is alerting people to the risks of contracting hepatitis from unsafe blood, unsafe injections, and sharing drug-injection equipment. Some 11 million people who inject drugs have hepatitis B or C infection. Children born to mothers with hepatitis B or C and sex partners of people with hepatitis are also at risk of becoming infected.

      The Organization emphasizes the need for all health services to reduce risks by using only sterile equipment for injections and other medical procedures, to test all donated blood and blood components for hepatitis B and C (as well as HIV and syphilis) and to promote the use of the hepatitis B vaccine. Safer sex practices, including minimizing the number of partners and using barrier protective measures (condoms), also protect against transmission.

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      Demand safe injections

      Approximately, two million people a year contract hepatitis from unsafe injections. These infections can be averted through the use of sterile syringes that are specifically designed to prevent reuse. Eliminating unnecessary injections is also an effective strategy to protect against hepatitis transmission. There are 16 billion injections administered every year. Around 5% of these injections are for immunization, a further 5% for procedures like blood transfusions and injectable contraceptives, and the remaining 90% to administer medicines. For many diseases, injections are not the first recommended course of treatment and oral medications could be used.

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      Be vaccinated

      WHO recommends vaccinating all children against hepatitis B infection, from which approximately 780 000 people die each year. A safe and effective vaccine can protect from hepatitis B infection for life. Ideally, the vaccine should be given as soon as possible after birth, preferably within 24 hours. The birth dose should be followed by 2 or 3 doses to complete the vaccine series.

      WHO also recommends vaccinating adults who are at increased risk of acquiring hepatitis B. These include people who frequently require blood or blood products (for example dialysis patients), health-care workers, people who inject drugs, household and sexual contacts of people with chronic hepatitis B, and people with multiple sexual partners.

      Since 1982, over 1 billion doses of hepatitis B vaccine have been used worldwide and millions of future deaths from liver cancer and cirrhosis have been prevented. In a number of countries where around 1 in 10 children used to become chronically infected with the hepatitis B virus, vaccination has reduced the rate of chronic infection to less than 1 in 100 among immunized children. To date, there is no available vaccine against hepatitis C.

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      Get tested, seek treatment

      Burials in common graves and mass cremations are rarely warranted and should be avoided.

      Medicines are now available that can cure most people with hepatitis C and control hepatitis B infection. People who receive these medicines are much less likely to die from liver cancer and cirrhosis and much less likely to transmit the virus to others. WHO therefore urges people who think they might have been exposed to hepatitis to get tested so they can find out whether they need treatment to improve their own health and reduce the risk of transmission.

      Earlier this year, WHO issued new guidelines for treatment of hepatitis B infection. These recommend using simple non-invasive tests to assess the stage of liver disease to help identify who needs treatment. WHO also calls for prioritizing treatment for those with cirrhosis - the most advanced stage of liver disease and for the use of two safe and highly effective medicines, tenofovir or entecavir. Continued monitoring using simple tests is important to assess whether treatment is working, and if it can be stopped.

      In 2014, WHO issued guidance for testing and treatment of hepatitis C infection. WHO recommends providing testing for people considered at high risk of infection and ensuring treatment for those who have the virus with several effective medicines, including new regimens that use only oral medicines. WHO will update recommendations on drug treatments periodically as new antiviral medicines become available and as new evidence emerges.

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      13. World Hepatitis Day 2015

      This year, WHO’s flagship event takes place in Egypt, a country that has one of the world’s highest hepatitis burdens. It is estimated that 10% of the ‎population between 15 and ‎‎59 years is chronically ‎infected with hepatitis C. Between 2007 and 2014, more than 350 000 people with hepatitis C have been treated. Since the introduction of newer, more effective medicines in 2014, the number of people being treated continues to increase. Today, 32 dedicated treatment centres are providing treatment at the Government’s expense. ‎Egypt is also highlighting hepatitis prevention. WHO is helping the country develop national ‎blood safety standards and has selected ‎it as one of 3 pilot ‎countries for its new Global ‎Injection Safety Initiative.‎ WHO will provide support over the next 3 years to ‎reduce unnecessary ‎injections and help transition to ‎the exclusive use of syringes ‎that can only be used once.

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      Global momentum to tackle hepatitis

      In September this year, countries will have the opportunity to share best practice at the first-ever World Hepatitis Summit to be held in Glasgow, Scotland. The summit, which is co-sponsored by WHO, the Scottish Government and the World Hepatitis Alliance, aims to raise the global profile of viral hepatitis, to create a platform for exchange of country experiences and to focus on working with countries to develop national action plans.